Antonio Conte’s side have secured six home league wins in a row and are the division’s best side on current form after Pep Guardiola’s all-conquering Manchester City.
The Blues face a trip to Arsenal on Wednesday night and have rotated their squad ahead of their visit to the Emirates Stadium.
Stoke, meanwhile, arrive at Stamford Bridge with the league’s worst defensive record and are without the injured trio of Ryan Shawcross, Bruno Martins Indi and Glen Johnson.
On-loan defender Kurt Zouma will have to watch from the sidelines due to him being unable to play against his parent club.
So, who has been selected for the clash at Stamford Bridge? The confirmed teams can be seen, in full, below…
Chelsea XI: Courtois, Azpilicueta, Cahill, Rudiger; Moses, Kante, Drinkwater, Alonso, Willian, Morata, Pedro
Substitutes: Caballero, Fabregas, Hazard, Bakayoko, Zappacosta, Batshuayi, Christensen
Stoke XI: Butland, Edwards, Cameron, Wimmer, Tymon, Fletcher, Adam, Diouf, Afellay, Sobhi, Berahino
Substitutes: Allen, Choupo-Moting, Shaqiri, Crouch, Ngoy, Grant, Soutar